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Asymmetric Direct Vinylogous Aldol Reaction of Furanone Derivatives Catalyzed by an Axially Chiral Guanidine Base

✍ Scribed by Hitoshi Ube; Naoki Shimada; Masahiro Terada

No coin nor oath required. For personal study only.

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Scheme 1. Construction of g-butenolides and glycerol derivatives through the vinylogous aldol reaction.

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