Asymmetric Desymmetrization of 2-Substituted 1,3-Propanediols via Catalytic Enantioselective Ring-Cleavage Reaction of Cyclic Acetal Derivatives.
β Scribed by Toshiro Harada; Koudai Shiraishi
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 25 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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Desymmetrization of meso-1,2-Diols via Chiral Oxazaborolidine-Mediated Ring-Cleavage of Acetal Derivatives with Silyl Ketene S,O-Acetal. -The desymmetrization of a variety of meso-1,2-diols is readily achieved by chiral oxazaborolidine-mediated enantioselective ring cleavage of acetals of type syn-
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