Asymmetric catalysis. Asymmetric catalytic intramolocular hydrosilation and hydroacylation

✍ Scribed by Richard W. Barnhart; Xianqi Wang; Pedro Noheda; Steven H. Bergens; John Whelan; B. Bosnich

• Book ID: 104204745
• Publisher: Elsevier Science
• Year: 1994
• Tongue: French
• Weight: 785 KB
• Volume: 50
• Category: Article
• ISSN: 0040-4020
• DOI: 10.1016/s0040-4020(01)89370-4

✦ Synopsis

Gztatysfs o/the lypt [Rh(chiml diphosphbw)]* e#cient& cata&se the Wamokukarhybosikuion ojsi&l ethers derirrd jivm al&lic alcohols. l%e pmducts can be unwetted to chimlI,3-aWs. Ii@ emwkmwic acess~ (ee's) on obsenwd for substmtes bea&g an a@ mp at the ole,iin terminus. lkse same catalysts pmduce chill

cycroPmtclnones fronr 4substituted 4-paw&. TemrUy. acyl and estersubstituentsgive neat@ quandtative ee's. lke mechanism of hydmsiiakm is infened to inwlvs sityi oI& bwem'an, whaas the kq step in hydmacyladoa pmbably imwlves reductive elimbwtion of the metallaq&heumone intennedkte.