Asymmetric Borane Reduction of Prochiral Ketones Using Imidazolium-Tagged Sulfonamide Catalyst.
β Scribed by Shang-Dong Yang; Yun Shi; Zhen-Hua Sun; Ya-Bin Zhao; Yong-Min Liang
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 22 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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π SIMILAR VOLUMES
Easily available D-(+)-camphor-derived chiral mercapt\*alcohols 2 and 3 were employed for catalytic asymmetric borane reduction of aromatic ketones. Moderate enantioselectivities with e.e. 20.2-72.1% were obtained with 10 mol% catalyst. Opposite asymmetric induction was achieved' when mercaptc-alcoh
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