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Asymmetric Alkaloid Synthesis: A One-Pot Organocatalytic Reaction to Quinolizidine Derivatives

✍ Scribed by Johan Franzén; Andreas Fisher

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
365 KB
Volume
48
Category
Article
ISSN
0044-8249

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✍ Henrik Sundén; Ramon Rios; Ismail Ibrahem; Gui-Ling Zhao; Lars Eriksson; Armando 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 188 KB 👁 2 views

## Abstract The highly enantioselective organocatalytic domino aza‐Michael/aldol reaction is presented. The unprecedented, chiral amine‐catalyzed asymmetric domino reactions between 2‐aminobenzaldehydes and α,β‐unsaturated aldehydes proceed with excellent chemo‐ and enantioselectivity to give the c