Enantioselective addition of (Z)- and (E
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Wolfgang Oppolzer; Rumen N. Radinov
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Article
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1991
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Elsevier Science
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French
β 249 KB
In situ prepared (Z)-and (E)-1 -alkenylzinc bromides 5 were added to various aldehydes 1 in the presence of lithiated (+)-N-methylephedrine or (+)-2-(NJ-dimethylamino)-1,2\_diphenylethanol to give sec. allylalcohols 7 in high optical purity with simple recovery of the chiral amino1 6. Asymmetric lig