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Asymmetric [3H]-labeling using ruthenium catalyzed transfer hydrogenation

✍ Scribed by Steve Arns; Anne Moreau; Robert N. Young

Publisher
John Wiley and Sons
Year
2010
Tongue
French
Weight
88 KB
Volume
53
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

The first general method for asymmetric tritiation using ruthenium catalyzed transfer hydrogenation and its application to the radiosynthesis of an exemplary prostaglandin EP4 receptor‐selective Prostaglandin E~2~ analog is described. The methodology should be of general utility for the enantioselective preparation of α‐tritiated chiral secondary alcohols. Copyright Β© 2010 John Wiley & Sons, Ltd.

πŸ“œ SIMILAR VOLUMES

ChemInform Abstract: Ruthenium-Catalyzed
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✍ K. EVERAERE; J.-F. CARPENTIER; A. MORTEUX; M. BULLIARD πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 32 KB πŸ‘ 1 views

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