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Asymmetric 1,2-addition of organolithiums to aldimines catalyzed by chiral ligand

✍ Scribed by Isao Inoue; Mitsuru Shindo; Kenji Koga; Kiyoshi Tomioka

Publisher
Elsevier Science
Year
1994
Tongue
French
Weight
705 KB
Volume
50
Category
Article
ISSN
0040-4020

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✦ Synopsis

An asymmetric 1,2-addition reaction of organolithiums with imines 3, 7 was catalyzed by a 0.05-1.3 equivalent of a chiral amino ether 2 to provide the corresponding optically active amines 4, 8.

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