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Astroglial cells inhibit inducible nitric oxide synthase and not interleukin-1β production by microglial cells

✍ Scribed by V.A.M. Vincent; A.N.M. Schoffelmeer; H.W.M. Steinbusch; F. Berkenbosch

Book ID
119109208
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
156 KB
Volume
54
Category
Article
ISSN
0165-5728

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In mixed glial cell cultures from cerebral cortices of newborn rats, endotoxin induces inducible nitric oxide (iNOS), nitric oxide (NO), and interleukin-1 beta (IL-1 beta) production in microglial cells. Earlier we demonstrated that endotoxin induced iNOS but not IL-1 beta expression in microglial c