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Astroglial and cognitive effects of chronic cerebral hypoperfusion in the rat

✍ Scribed by Évelin Vicente; Daniel Degerone; Liana Bohn; Francisco Scornavaca; Alexandre Pimentel; Marina C. Leite; Alessandra Swarowsky; Letícia Rodrigues; Patrícia Nardin; Lucia Maria Vieira de Almeida; Carmem Gottfried; Diogo Onofre Souza; Carlos Alexandre Netto; Carlos Alberto Gonçalves

Book ID
113503972
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
638 KB
Volume
1251
Category
Article
ISSN
0006-8993

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## Abstract Chronic cerebral hypoperfusion has been suggested to contribute to the progression of dementia. Inflammation and white matter lesion (WML) are involved in the pathologic process. This study investigated whether huperzine A, a natural acetylcholinesterase (AChE) inhibitor, has beneficial