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Astrocytic-neuronal crosstalk: Implications for neuroprotection from brain injury

✍ Scribed by George E. Barreto; Janneth Gonzalez; Yolima Torres; L. Morales


Book ID
115547867
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
403 KB
Volume
71
Category
Article
ISSN
0168-0102

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## Abstract We recently demonstrated that interleukin‐1Ξ² (IL‐1Ξ²) increases system x~c~^βˆ’^ (cystine/glutamate antiporter) activity in mixed cortical cell cultures, resulting in an increase in hypoxic neuronal injury when glutamate clearance is impaired. Herein, we demonstrate that neurons, astrocyte