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Astrocytic function and its alteration in the epileptic brain

✍ Scribed by Ronald Jabs; Gerald Seifert; Christian Steinhäuser

Book ID
109110724
Publisher
Wiley (Blackwell Publishing)
Year
2008
Tongue
English
Weight
460 KB
Volume
49
Category
Article
ISSN
0013-9580

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Diffusely infiltrating low-grade astrocytomas (WHO grade II) have an intrinsic tendency for progression to anaplastic astrocytoma (WHO grade III) and glioblastoma (WHO grade IV). This change is due to the sequential acquisition of genetic alterations, several of which have recently been identified.