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Astrocytes facilitate the growth and differentiation of co-cultured mesenchymal stem cells

✍ Scribed by Qian Chu; Zhiyuan Yu; Suming Zhang; Shiying Yu


Book ID
107405782
Publisher
Springer-Verlag
Year
2008
Tongue
Chinese
Weight
330 KB
Volume
28
Category
Article
ISSN
0510-9752

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The cardiomyocyte (CM) differentiation of embryonic stem cells (ESCs) is routinely cultured as two-dimensional (2D) monolayer, which doesn't mimic in vivo physiological environment and may lead to low differentiated level of ESCs. Here, we develop a novel strategy that enhances CM differentiation of