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Astrocytes Control Breathing Through pH-Dependent Vesicular Release of Atp

✍ Scribed by Kasymov, Vitaliy; Marina, Nephtali; Kasparov, Sergey; Gourine, Alexander V.

Book ID
119206695
Publisher
Biophysical Society
Year
2010
Tongue
English
Weight
119 KB
Volume
98
Category
Article
ISSN
0006-3495

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## Abstract Nitric oxide (NO; 1 μM) or an NO donor (500 μM diethylenetriamine‐nitric oxide, DETA‐NONOate) caused rapid glutamate and ATP release from cultured rat cortical astrocytes. NO‐induced glutamate release was prevented by calcium chelators (EGTA or BAPTA‐AM) and an inhibitor of vesicular ex