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Astrocytes and central nervous system endothelial cells do not express B7-1 (CD80) or B7-2 (CD86) immunoreactivity during experimental autoimmune encephalomyelitis

โœ Scribed by Anne H Cross; Grace Ku


Book ID
114137198
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
866 KB
Volume
110
Category
Article
ISSN
0165-5728

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T cell co-stimulation through the CD28 receptor on T cells is critical to the induction of experimental autoimmune encephalomyelitis (EAE). In this study, expression of the co-stimulatory ligands B7-1 (CD80) and B7-2 (CD86), as well as the receptors CD28 and CTLA-4, were quantitated in central nervo