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Astrocyte-Enhanced Neuronal Survival is Mediated by Scavenging of Extracellular Reactive Oxygen Species

✍ Scribed by Benjamin Drukarch; Eric Schepens; Johannes C. Stoof; Cornelis H. Langeveld; Freek L. Van Muiswinkel


Book ID
114276909
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
105 KB
Volume
25
Category
Article
ISSN
0891-5849

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## Abstract Generation of reactive oxygen species (ROS) in brain tissue leads to neurodegeneration. The major source of ROS is the mitochondrial respiratory chain. We studied regulation of Ca^2+^ level, mitochondrial potential, and ROS generation in defined mixed hippocampal cell cultures exposed t