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Astrocyte elevated gene-1 activates cell survival pathways through PI3K-Akt signaling

✍ Scribed by Lee, S-G; Su, Z-Z; Emdad, L; Sarkar, D; Franke, T F; Fisher, P B

Book ID
110072703
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
280 KB
Volume
27
Category
Article
ISSN
0950-9232

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## Abstract Activated phosphoinositide 3‐kinase (PI3K) and its downstream target Akt/PKB are important signaling molecules and key survival factors involved in the control of cell proliferation, apoptosis and oncogenesis. We investigated the role of the PI3K‐Akt signaling pathway in the invasion of