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Astilbin suppresses collagen-induced arthritis via the dysfunction of lymphocytes

✍ Scribed by Y. Cai; T. Chen; Q. Xu


Publisher
SP Birkhäuser Verlag Basel
Year
2003
Tongue
English
Weight
182 KB
Volume
52
Category
Article
ISSN
1420-908X

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The co-ordinate role of the Th1 cytokine IL-12 and the proinflammatory cytokine TNF in arthritis was explored using the DBA/1 mouse model, collagen-induced arthritis (CIA). In this study, mice with established arthritis were treated with anti-IL-12 and/or anti-TNF antibodies for 10 days from the ons