Asthma Treatment: A Multidisciplinary Approach

✍ Scribed by Peter K. Jeffery (auth.), D. Olivieri, P. J. Barnes, S. S. Hurd, G. C. Folco (eds.)

• Publisher: Springer US
• Year: 1992
• Tongue: English
• Leaves: 292
• Series: NATO ASI Series 229
• Edition: 1
• Category: Library

✦ Synopsis

From the 19-29 May 1991 the NATO ASI Course PAsthma Treatment: A P Multidisciplinary Approach was held in Erice, on the rocky North West Coast of Sicily, facing the ancient Phoenician shore of the African Continent. Sixty NATO sponsored participants arriving from many different European Countries - Nato members and non - attended the course. Qualified researchers from Europe and the United States held extensive lectures, short meetings and small informal group discussions. Erice is a magical place which draws together people from different backgrounds and cultures under her Mediterrean charm, recreating the ancient Greek openair discussion atmosphere. And so, during the 10 days gathering, the extensive willingness of the senior investigators and the laudable enthusiasm of the younger participants was stimulated. All of the most recent findings in the biology and the pharmacology of Asthma were discussed, initially behind closed doors, to be unhurriedly continued along the alley ways of the "Cittadella della Scienza" , in Erice's small restaurants, and on her deserted beaches. The texts collected here are testimony to the high quality of the investigators contributions as well as their far reaching interests. I think that a Director of such a Course would be adequatly satisfied by merely considering the enthusiasm and high level involvement of every participant. He could not have been more satisfied after having considered the proceedings summerizing the scientific content of the meeting.

✦ Table of Contents

Front Matter....Pages i-ix
Histopathology of Bronchial Asthma and the Effects of Treatment....Pages 1-7
Neural Control of Airways....Pages 9-19
Airway Neuropeptides....Pages 21-50
Potential Role of Mast Cell Proteases in Asthma....Pages 51-61
Human Mast Cells, Basophils and Their Mediators....Pages 63-79
Platelets and Asthma....Pages 81-87
The Maximal Bronchoconstriction Induced by Methacholine is not Altered by Platelet Activating Factor....Pages 89-92
Leukotrienes and Asthma....Pages 93-103
Plasma Exudation in Asthma and Its Pharmacological Control....Pages 105-116
Synthesis and Regulation of IgE in Asthma....Pages 117-129
Modulation of Mediator Release From Human FcεRI + Cells....Pages 131-144
Osmotic and Ionic Factors in Bronchial Responsiveness....Pages 145-154
Airway Responsiveness, Late-Phase Response, and Inflammation in Allergic Asthma....Pages 155-160
Injury and Repair of the Airway Epithelium in Asthma....Pages 161-170
Bronchoalveolar Lavage: Its Application in Asthma....Pages 171-182
Bronchial Asthma and Pulmonary Gas Exchange....Pages 183-187
Allergen Inhalation Increases Cough Sensitivity in Subjects with Allergic Asthma....Pages 189-192
Asthma Management....Pages 193-206
The National Asthma Education Program....Pages 207-214
Management of Asthmatic Children....Pages 215-229
Inhaled Corticosteroids in the Long Term Treatment of Asthma and COPD....Pages 231-236
Sympathomimetics and Xanthines in the Treatment of Asthma....Pages 237-255
Protective Effect of Furosemide, Administered Using a Pressurized Metered Dose Inhaler and a Spacer Device, on the Bronchial Obstructive Response to Ultrasonically Nebulized Distilled Water....Pages 257-260
Frusemide Inhalation Prevents Immunological Mediator Release and Respiratory Changes in Guinea-Pig....Pages 261-271
Pharmacological Profile of CR 2039 (Dizolast) a New Agent for the Treatment of Allergic Diseases....Pages 273-277
Effect of Betaxolol on Bronchial Responsiveness in Mild Asthmatic Subjects with Chronic Glaucoma: A Pilot Study....Pages 279-284
Mast Cells and Eosinophils in Bronchial Asthma....Pages 285-294
Back Matter....Pages 295-295

✦ Subjects

Cardiology;Pharmacology/Toxicology;Animal Physiology;Biophysics and Biological Physics