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Associations of xenobiotic-metabolizing enzyme genotypes PON1Q192R, PON1L55M and CYP1A1*2A MspI with pathological symptoms of a rural population in south Greece

✍ Scribed by Tsatsakis, Aristidis M.; Androutsopoulos, Vasilis P.; Zafiropoulos, Alexandros; Babatsikou, Fotoula; Alegakis, Thanasis; Dialyna, Ioanna; Tzatzarakis, Manolis; Koutis, Charilaos

Book ID
115533066
Publisher
Informa plc
Year
2011
Tongue
English
Weight
724 KB
Volume
41
Category
Article
ISSN
0049-8254

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## Abstract Paraoxonase 1 (PON 1) is a high‐density lipoprotein (HDL)‐associated enzyme with antioxidant function protecting low‐density lipoprotein (LDL) from oxidation. PON 1 has two amino acid polymorphisms in coding region; L/M 55 and Q/R 192. These polymorphisms modulate paraoxonase activity o