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Associations of allelic variants of the multidrug resistance gene (ABCB1 or MDR1) and Inflammatory Bowel Disease and their effects on disease behavior: A case-control and meta-analysis study

✍ Scribed by Clive M. Onnie; Sheila A. Fisher; Reenal Pattni; Jeremy Sanderson; Alastair Forbes; Cathryn M. Lewis; Prof. Christopher G. Mathew

Book ID: 110087379
Publisher: John Wiley and Sons
Year: 2006
Tongue: English
Weight: 215 KB
Volume: 12
Category: Article
ISSN: 1078-0998
DOI: 10.1097/01.mib.0000209791.98866.ba

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Is there evidence to claim or deny association between variants of the multidrug resistance gene (MDR1 or ABCB1) and inflammatory bowel disease?

✍ Elias Zintzaras 📂 Article 📅 2012 🏛 John Wiley and Sons 🌐 English ⚖ 984 KB

Background: Inflammatory bowel disease (IBD) is a complex disease with a genetic background. Crohn's disease (CD) and ulcerative colitis (UC) are the two main types of IBD. There is indication that variants in the MDR1 gene are associated with development of IBD. However, the 20 published genetic as