## Abstract Case‐control genome‐wide association studies provide a vast amount of genetic information that may be used to investigate secondary phenotypes. We study the situation in which the primary disease is rare and the secondary phenotype and genetic markers are dichotomous. An analysis of the
✦ LIBER ✦
Associations Between Incident Ischemic Stroke Events and Stroke and Cardiovascular Disease-Related Genome-Wide Association Studies Single Nucleotide Polymorphisms in the Population Architecture Using Genomics and Epidemiology Study
✍ Scribed by Carty, C. L.; Buzkova, P.; Fornage, M.; Franceschini, N.; Cole, S.; Heiss, G.; Hindorff, L. A.; Howard, B. V.; Mann, S.; Martin, L. W.
- Book ID
- 115477887
- Publisher
- Ovid Technologies Wolters Kluwer -American Heart Association
- Year
- 2012
- Tongue
- English
- Weight
- 91 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1942-325X
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## Abstract ## Objective To perform a large‐scale association analysis of single‐nucleotide polymorphisms (SNPs) in patients with radiographically defined osteoarthritis (OA) of the knee. ## Methods We examined >25,000 SNPs located within ∼14,000 genes for associations with radiographically defi