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Associations between HDL oxidation and paraoxonase-1 and paraoxonase-1 gene polymorphisms in families affected by familial combined hyperlipidemia

✍ Scribed by M.-L. Liu; R.W. James; K. Ylitalo; M.-R. Taskinen

Book ID
117638448
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
606 KB
Volume
14
Category
Article
ISSN
0939-4753

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## Abstract Paraoxonase 1 (PON1) is a serum enzyme closely associated with high‐density lipoprotein (HDL), which may protect against atherosclerosis by hydrolyzing lipid peroxides and several organophosphorus compounds. The purpose of the present study was to test the hypothesis that lipid peroxida