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Associations among telomerase activity, p53 protein overexpression, and genetic instability in lung cancer

✍ Scribed by Wu, X; Kemp, B; Amos, C I; Honn, S E; Zhang, W; Walsh, G L; Spitz, M R


Book ID
110002195
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
173 KB
Volume
80
Category
Article
ISSN
0007-0920

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## Abstract In order to reveal whether differences in the type and site of __p53__ gene mutations influence the function of the gene and tumor phenotype, we examined nuclear accumulation of the p53 protein immunohistochemically, loss of the other p53 allele by restriction‐fragment‐length polymorphi