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Association study of polymorphisms in LRP1, tau and 5-HTT genes and Alzheimer’s disease in a sample of Colombian patients

✍ Scribed by D. A. Forero; G. Arboleda; J. J. Yunis; R. Pardo; H. Arboleda

Book ID
106206918
Publisher
Springer
Year
2005
Tongue
English
Weight
96 KB
Volume
113
Category
Article
ISSN
1435-1463

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## Abstract Alzheimer's disease (AD) is characterized by an extensive loss of cholinergic neurons, and their cortical projections, from the basal forebrain area. The resulting reduction in cholinergic activity is associated with decreased levels of the neurotransmitter acetylcholine (ACh), decrease