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Association study of candidate variants of COMT with neuroticism, anxiety and depression

✍ Scribed by Naomi R. Wray; Michael R. James; Troy Dumenil; Herlina Y. Handoko; Penelope A. Lind; Grant W. Montgomery; Nicholas G. Martin


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
68 KB
Volume
147B
Category
Article
ISSN
1552-4841

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Several linkage studies suggested chromosome 22q11-13 may harbor susceptible genes for schizophrenia. Catechol-0methyl-transferase t:COMT), which is involved in the metabolism of catecholamines, was mapped to 22q'll and is considered a possible candidate gene for schizophrenia. Recently, we identifi