Association Study Between the 441C Ins/Del and TaqI A Polymorphisms of the Dopamine D2 Receptor Gene and Alcoholism
β Scribed by Hiroki Ishiguro; Tadao Arinami; Toshikazu Saito; Shigeru Akazawa; Minoru Enomoto; Hiroshi Mitushio; Hiroshi Fujishiro; Kunimaro Tada; Yutaka Akimoto; Hideo Mifune; Shinichi Shioduka; Hideo Hamaguchi; Michio Toru; Haruo Shibuya
- Book ID
- 109120037
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 422 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0145-6008
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
We examined the allelic association between the dopamine D2 receptor (DRD2) gene and alcoholism in 100 biologically unrelated Japanese alcoholics and 93 unrelated controls. Genomic DNA was prepared from peripheral white blood cells using the phenol-chloroform method. A 310-bp region surrounding the
The human dopamine D 2 receptor gene (DRD 2 ) has received considerable attention for the past several years as a potential candidate that may affect susceptibility to alcoholism. The association studies that compared the frequencies of alleles of DRD 2 gene between alcoholics and control groups hav
To address the controversy surrounding DRDS and alcoholism, we performed linkage and association studies utilizing alcoholic men from high-density families largely uncontaminated by other psychopathology and female alcoholics for whom secondary drug dependence (averaging 10 years later onset) was a