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Association strategies in Alzheimer's disease: Findings from the NIMH genetics initiative

✍ Scribed by Deborah Blacker; Rudolph E. Ranzi; Nan M. Laird

Book ID
117411567
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
166 KB
Volume
21
Category
Article
ISSN
0197-4580

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## Abstract We performed linkage analysis for age at onset (AAO) in the total Alzheimer's disease (AD) NIMH sample (N = 437 families). Families were subset as late‐onset (320 families, AAO β‰₯65) and early/mixed (117 families, at least 1 member with 50< AAO <65). Treating AAO as a censored trait, we