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Association of Urinary Type IV Collagen With GFR Decline in Young Patients With Type 1 Diabetes

✍ Scribed by Miwa Morita; Yasuko Uchigata; Ko Hanai; Yohei Ogawa; Yasuhiko Iwamoto

Book ID
114470569
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
518 KB
Volume
58
Category
Article
ISSN
0272-6386

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## Abstract To investigate the changes of renal type IV collagen turnover in diabetic nephropathy, urinary type IV collagen was measured by a highly sensitive one‐step sandwich enzyme immunoassay (EIA). Urinary samples were obtained from 698 diabetic patients and 191 healthy adults. Among the patie

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Type IV collagen is a major component released from the glomerular and tubular basement membranes. To investigate the alteration of renal type IV collagen turnover in early stage diabetic nephropathy, urinary type IV collagen was measured by a highly sensitive one-step sandwich enzyme immunoassay (E