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Association of two polymorphisms of theIL28Bgene with viral factors and treatment response in 1,518 patients infected with hepatitis C virus

✍ Scribed by Mariko Kobayashi, Fumitaka Suzuki, Norio Akuta, Hitomi Sezaki, Yoshiyuki Suzuki, Tetsuya Hosaka, Yusuke Kawamura, Masahiro Kobayashi, Satoshi Saitoh, Yasuji Arase, Kenji Ikeda, Kazuaki Chayama, Yuzo Miyakawa, Hiromitsu Kumada

Book ID
111936956
Publisher
Springer Japan
Year
2012
Tongue
English
Weight
491 KB
Volume
47
Category
Article
ISSN
0944-1174

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Polymorphism in the interleukin-28B (IL28B) gene region, encoding interferon (IFN)-k3, is strongly predictive of response to antiviral treatment in the nontransplant setting. We sought to determine the prevalence and impact on clinical outcomes of donor and recipient IL28B genotypes among liver tran