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Association of TNF -238 and -308 Promoter Polymorphisms with Psoriasis Vulgaris and Psoriatic Arthritis but not with Pustulosis Palmoplantaris

✍ Scribed by Mossner, Rotraut; Kingo, Kulli; Kleensang, Andre; Kruger, Ullrich; Konig, Inke R.; Silm, Helgi; Westphal, Gotz A.; Reich, Kristian

Book ID: 110733376
Publisher: Nature Publishing Group
Year: 2005
Tongue: English
Weight: 75 KB
Volume: 124
Category: Article
ISSN: 0022-202X
DOI: 10.1111/j.0022-202x.2004.23556.x

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## Abstract ## Objective Single‐nucleotide polymorphisms (SNPs) of the tumor necrosis factor gene __TNF__ at positions −238 and −308 have been associated with psoriasis vulgaris and psoriatic arthritis (PsA). The strong linkage disequilibrium (LD) at chromosome region 6p21, a region known to harbo

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