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Association of the RAGE G82S polymorphism with Alzheimer’s disease

✍ Scribed by Jonny Daborg; Malin von Otter; Annica Sjölander; Staffan Nilsson; Lennart Minthon; Deborah R. Gustafson; Ingmar Skoog; Kaj Blennow; Henrik Zetterberg

Publisher
Springer
Year
2010
Tongue
English
Weight
210 KB
Volume
117
Category
Article
ISSN
1435-1463

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## Abstract Alzheimer's disease (AD) is a polygenic and multifactorial complex disease, whose etiopathology is still unclear, however several genetic factors have shown to increase the risk of developing the disease. Purine nucleotides and nucleosides play an important role in the brain. Besides th