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Association of Tef polymorphism with depression in Parkinson disease

✍ Scribed by Hua, Ping; Liu, Weiguo; Kuo, Sheng-Han; Zhao, Yanyan; Chen, Ling; Zhang, Ning; Wang, Chun; Guo, Suwan; Wang, Li; Xiao, Hong; Kwan, Justin Y.; Wu, Tianxia

Book ID: 118764301
Publisher: John Wiley and Sons
Year: 2012
Tongue: English
Weight: 114 KB
Volume: 27
Category: Article
ISSN: 0885-3185
DOI: 10.1002/mds.25195

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## Abstract The presynaptic dopamine transporter in nigral dopaminergic neurons confers susceptibility to the cytotoxic effects of the neurotoxic metabolite of 1‐methy1‐4‐phenyl‐1,2,3,6‐tetrahydropyridine. Polymorphisms in the dopamine transporter might influence the susceptibility to such toxins.