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Association of some rare haplotypes and genotype combinations in the MDR1 gene with childhood acute lymphoblastic leukaemia

✍ Scribed by Ágnes F. Semsei; Dániel J. Erdélyi; Ildikó Ungvári; Enikő Kámory; Béla Csókay; Hajnalka Andrikovics; Attila Tordai; Edit Cságoly; András Falus; Gábor T. Kovács; Csaba Szalai


Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
115 KB
Volume
32
Category
Article
ISSN
0145-2126

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The aim of this study is to determine whether the polymorphisms of the MDR1 gene are associated with the development of childhood acute lymphoblastic leukemia (ALL). The MDR1 gene polymorphisms, -2352 G>A, -934A>G, -692T>C (5' regulatory region) and 3435C>T (exon 26), were examined in 157 ALL patien