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Association of single nucleotide polymorphisms inMTHFRandABCG2with the different efficacy of first-line chemotherapy in metastatic colorectal cancer

✍ Scribed by Zhao, Jing; Li, Wenhua; Zhu, Dan; Yu, Qihe; Zhang, Zhe; Sun, Menghong; Cai, Sanjun; Zhang, Wen

Book ID
121577993
Publisher
Springer US
Year
2013
Tongue
English
Weight
256 KB
Volume
31
Category
Article
ISSN
1357-0560

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## Abstract ## BACKGROUND CpG island hypermethylation has been reported at the promoter region of many tumor suppressor genes in colorectal cancers. However, there are significant interindividual differences in the degree of DNA methylation in colorectal cancers. The objective of the current study