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Association of serum alkaline phosphatase and bone mineral density in maintenance hemodialysis patients

โœ Scribed by Jong Chan PARK; Csaba P. KOVESDY; Uyen DUONG; Elani STREJA; Mehdi RAMBOD; Allen R. NISSENSON; Stuart M. SPRAGUE; Kamyar KALANTAR-ZADEH


Book ID
109227685
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
196 KB
Volume
14
Category
Article
ISSN
1492-7535

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Rare coding variants in ALPL are associa
โœ Carrie M Nielson; Joseph M Zmuda; Amy S Carlos; Wendy J Wagoner; Emily A Larson; ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› American Society for Bone and Mineral Research ๐ŸŒ English โš– 415 KB

## Abstract Alkaline phosphatase (ALP) plays an essential role in the regulation of tissue mineralization, and its activity is highly heritable. Guided by genetic associations discovered in a murine model, we hypothesized a role for rare coding variants in determining serum ALP level and bone miner