## Abstract Previous studies have indicated associations between a functional biallelic repetitive element in the 5β² regulatory region of the serotonin transporter gene (5βHTTLPR) and alcoholic subjects who have either dissocial personality disorder or severe withdrawal symptoms. To replicate these
Association of serotonin transporter regulatory region polymorphism and abnormal eating behaviors
β Scribed by Matsushita, S; Nakamura, T; Nishiguchi, N; Higuchi, S
- Book ID
- 110059393
- Publisher
- Nature Publishing Group
- Year
- 2002
- Tongue
- English
- Weight
- 70 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1359-4184
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## Abstract The pathophysiological mechanisms underlying binge eating disorder (BED) are poorly understood. There is evidence that abnormalities in brain serotonin (5HT) play an important role in binge eating behavior, therefore genes involved in 5HT transmission, such as the 5HT transporter (5HTT)
## Abstract ## **Objective:** The serotonin system has been implicated in mood and appetite regulation, and the serotonin transporter gene (__SLC6A4__) is a commonly studied candidate gene for eating pathology. However, most studies have focused on a single polymorphism (__5βHTTLPR__) in __SLC6A4_