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Association of PTPN22 gene (rs2488457) polymorphism with ulcerative colitis and high levels of PTPN22 mRNA in ulcerative colitis

✍ Scribed by Zhitao Chen, Heng Zhang, Bing Xia, Ping Wang…

Book ID
120793762
Publisher
Springer
Year
2013
Tongue
English
Weight
187 KB
Volume
28
Category
Article
ISSN
0179-1958

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## Background: The PTPN22 gene is an important risk factor for human autoimmunity. The aim of this study was to evaluate for the first time the role of the R263Q PTPN22 polymorphism in ulcerative colitis (UC) and Crohn's disease (CD), and to reevaluate the association of the R620W PTPN22 polymorph