Taxol, a microtubule stabilizing agent, has been extensively investigated for its antitumor activity. The cytotoxic effect of taxol is generally attributed to its antimicrotubule activity and is believed to be cell cycle dependent. Herein, we report that taxol induces hyperphosphorylation and reorga
Association of protein phosphatase 2A with its substrate vimentin intermediate filaments in 9L rat brain tumor cells
โ Scribed by Ting-Jen Cheng; Yi-Liang Lin; Ann-Shyn Chiang; Yiu-Kay Lai
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 619 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0730-2312
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Organization of intermediate filament, a major component of cytoskeleton, is regulated by protein phosphorylation/dephosphorylation, which is a dynamic process governed by a balance between the activities of involved protein kinases and phosphatases. Blocking dephosphorylation by protein phosphatase
Induction of heat-shock proteins and glucose-regulated proteins in 9L rat brain tumor cells can be differentially elicited by sodium arsenite, cadmium chloride, zinc chloride, copper sulfate, sodium fluoride, and L-azetidine-2-carboxylic acid. The kinds of stress protein induced by the above chemica