Association of genotypes of carcinogen-a
โ
Shogo Ozawa; Takahiko Katoh; Hisato Inatomi; Hirohisa Imai; Yoshiki Kuroda; Masa
๐
Article
๐
2002
๐
John Wiley and Sons
๐
French
โ 203 KB
Carcinogenic aromatic amines such as 4-aminobiphenyl, which is contained in tobacco smoke, are one of the causal factors of urothelial epithelial cancers. 4-Aminobiphenyl has been shown to be bioactivated through N-hydroxylation by hepatic cytochrome (CYP) 1A2 and subsequently through O-sulfation an