Association of p53 gene mutations with sensitivity to TZT-1027 in patients with clinical lung and renal carcinoma

p53 Mutation and allelic loss of chromos

p53 Mutation and allelic loss of chromosome 3p, 9p of preneoplastic lesions in patients with nonsmall cell lung carcinoma

✍ Hiromasa Kohno; Kenzo Hiroshima; Tetsuya Toyozaki; Takehiko Fujisawa; Hidemi Ohw 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 169 KB 👁 1 views

## Background: An accumulation of mutations can result in carcinogenesis. comparing genetic alterations in preneoplastic lesions with those seen in cancer in the same patient may be helpful in the early diagnosis of lung carcinoma or preneoplastic lesions. ## Methods: To identify genetic alterati