Association of NAT2 Gene Polymorphisms with Susceptibility to Esophageal and Gastric Cancers in the Kashmir Valley
β Scribed by Manzoor Ahmad Malik; Rohit Upadhyay; Dinesh Raj Modi; Showket Ali Zargar; Balraj Mittal
- Book ID
- 113467320
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 152 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0188-4409
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The polymorphic arylamine N-acetyltransferases (NAT1 and NAT2) have been implicated in increased susceptibility to certain malignancies. We analyzed genetic polymorphisms in both the NAT1 and NAT2 genes among 140 gastric adenocarcinoma patients, 103 colorectal adenocarcinoma patients and 122 healthy
## Abstract Investigation of potential association of SNPs (G870A, rs9344; G1722C, rs678653) of cyclin D1 gene (__CCND1__) with susceptibility to esophageal squamous cell carcinoma (ESCC) in Kashmir valley (India). The study included 302 subjects comprising 151 ESCC cases and 151 controls. PCRβRFLP