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Association of modified cytosines and the methylated DNA-binding protein MeCP2 with distinctive structural domains of lampbrush chromatin

✍ Scribed by Garry T Morgan, Peter L Jones, Michel Bellini


Book ID
120705078
Publisher
BioMed Central
Year
2013
Tongue
English
Weight
83 KB
Volume
6
Category
Article
ISSN
1756-8935

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Methylated CpG Binding Protein 2 (MeCP2) is a nuclear protein named for its ability to selectively recognize methylated DNA. Much attention has been focused on understanding MeCP2 structure and function in the context of its role in Rett syndrome, a severe neurodevelopmental disorder that afflicts o