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Association of Mal/TIRAP S180L variant polymorphism with decreased infection risk in patients with advanced HIV-1 infection

✍ Scribed by Antonios I. Papadopoulos; Bart Ferwerda; Anastasia Antoniadou; Vissaria Sakka; Lambrini Galani; Dimitra Kavatha; Periklis Panagopoulos; Garyphalia Poulakou; Konstantinos Protopapas; Jos W.M. van der Meer; Mihai G. Netea; Evangelos J. Giamarellos-Bourboulis

Book ID: 119224859
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 170 KB
Volume: 60
Category: Article
ISSN: 1043-4666
DOI: 10.1016/j.cyto.2012.05.008

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## Abstract The clinical course and outcome of HIV‐1 infection are highly variable among individuals. Interleukin 4 (IL‐4) is a key T helper 2 cytokine with various immune‐modulating functions including induction of immunoglobulin E (IgE) production in B cells, downregulation of CCR5 and upregulati