Association of major histocompatibility complex class I chain-related gene A microsatellite polymorphism and hepatocellular carcinoma in South China Han population
β Scribed by X. Jiang; Y. Zou; Z. Huo; P. Yu
- Book ID
- 110893394
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 547 KB
- Volume
- 78
- Category
- Article
- ISSN
- 0001-2815
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The ectodomain of major histocompatibility complex class I-related chain A (MICA) is shed from tumor cells, and may be an important means of evading antitumor immunity. This study investigated the roles of a disintegrin and metalloproteinase 9 (ADAM9) in the shedding of MICA in human hepatocellular
## Background: Recent studies have demonstrated an association of a polymorphic (gct)n triplet repeat in the transmembrane (tm) region of the major histocompatibility complex (mhc) class i chain-related gene a (mica), one of the mhc class i chain-related (mic) family members, with some autoimmune d