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Association of MAD2 expression with mitotic checkpoint competence in hepatoma cells

✍ Scribed by Karen Man-Fong Sze; Yick-Pang Ching; Dong-Yan Jin; Irene Oi-Lin Ng

Book ID
105515902
Publisher
BioMed Central
Year
2004
Tongue
English
Weight
766 KB
Volume
11
Category
Article
ISSN
1021-7770

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## Abstract Aneuploidy and genetic instability are a hallmark of colorectal cancer and other solid tumors, and they are thought to enhance tumor progression. The gene __MAD2L____2__ (mitotic arrest deficient 2‐like 2) encodes the spindle checkpoint protein MAD2L2 (or MAD2B), a key component of a su