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Association of loss of heterozygosity on chromosome 13Q with hepatocellular carcinoma progression

✍ Scribed by Nakamori, S.; Fujiwara, Y.; Nagano, H.; Sakon, M.; Monden, M.; Sasaki, S.; Furukawa, H.; Imaoka, S.; Kuroki, T.; Nakamura, Y.


Book ID
123487181
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
166 KB
Volume
114
Category
Article
ISSN
0016-5085

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Frequent loss of heterozygosity on chrom
✍ Kazuhiro Takahashi; Jiro Kudo; Hiromi Ishibashi; Yasuhiko Hirata; Yoshiyuki Niho πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 665 KB

We investigated 24 hepatocellular carcinomas in Japan to find loss of heterozygosity with 15 polymorphic DNA markers that detect allelic losses at specific chromosome loci. Loss of heterozygosity on chromosomes lOq, 17p and 22q was detected in 3 of 12 (26%), 9 of 21 (43%) and 5 of 15 (33%) informati