Association of Lewy bodies and glial cytoplasmic inclusions in the brain of Parkinson's disease
β Scribed by Akihide Mochizuki; Yasuko Komatsuzaki; Shin'ichi Shoji
- Publisher
- Springer-Verlag
- Year
- 2002
- Tongue
- English
- Weight
- 481 KB
- Volume
- 104
- Category
- Article
- ISSN
- 0001-6322
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π SIMILAR VOLUMES
Dementia in Parkinson's disease (PDD) is a frequent and distressing complication with major consequences. Clinical and pathological features closely link PDD and dementia with Lewy bodies (DLB), suggesting they represent part of the same disease spectrum. Although dopaminergic deficiency primarily d
## Abstract In Parkinson's disease (PD) neuronal degeneration is associated with abnormal protein aggregation in various forms including Lewy bodies (LBs). A major component of LBs is Ξ±βsynuclein; septin 4 (SEPT4), a polymerizing GTPβbinding protein that serves as scaffold for diverse molecules has