Association of interleukin-6 gene G-174C polymorphism and plasma plasminogen activator inhibitor-1 level in Chinese patients with and without hypertension
β Scribed by Jing-Ren Jeng; Ji-Hung Wang; Wei-Shin Liu; Shee-Ping Chen; Michael Yu-Chih Chen; Meng-Hsiu Wu; Wen-Lin Hsu; Shinn-Zong Lin
- Book ID
- 116208512
- Publisher
- Nature Publishing Group
- Year
- 2005
- Tongue
- English
- Weight
- 105 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0895-7061
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## Background: Gene polymorphisms of proinflammatory cytokines, such as interleukin-6 (il-6) and the chemokine receptor cx3cr1, have been found in association with cardiovascular disease in the general population. in dialysis patients, in whom the prevalence of cardiovascular comorbidity is strikin
## Objective: To investigate the relationship between the 4g/5g polymorphism of the type 1 plasminogen activator inhibitor (pai-1) gene and thrombotic manifestations in patients with antiphospholipid syndrome (aps). ## Methods: We studied a total of 247 patients included in the following 4 groups