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Association of IL-6 promoter and IFN-γ gene polymorphisms with acute rejection of liver transplantation

✍ Scribed by Mohammad Hossein Karimi; Saeed Daneshmandi; Ali Akbar Pourfathollah; Bita Geramizadeh; Seyed Ali Malekhosseini; Saman Nikeghbalian; Ramin Yaghobi; Shahram Bolandparvaz

Publisher
Springer
Year
2010
Tongue
English
Weight
189 KB
Volume
38
Category
Article
ISSN
0301-4851

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Interferon-c (IFN-c) is a pleiotropic cytokine that plays an important role in regulating cellular immune responses. Regulation of IFN-c expression is considered to be strictly controlled at the transcriptional level. Two single-nucleotide polymorphisms (SNPs) within the human IFN-c promoter (at pos